![]() A similar association between AGR and cardiac and cerebrovascular events was found in a United States study and a Japanese study. In a United States study of 999 patients with heart failure, 1-year all-cause mortality in low AGR was associated with high. In a United States’ retrospective study of breast cancer, 5-year mortality in patients with high AGR was significantly lower than those with moderate and low AGR. In a Turkish retrospective study of 240 lung adenocarcinoma patients, AGR value was positively correlated with mean survival time. In a United States prospective cohort study of 534 patients with colorectal cancer, 4 years mortality in the lowest AGR was significantly higher compared to moderate and high AGR. All probability values for statistical tests were two-tailed, and a P-value of < 0.05 was considered statistically significant.ĪGR has been reported to be a prognostic marker in patients with cancer. ROC curve, sensitivity, specificity, and cutoff value of AGR were analyzed using JMP 14.2 (SAS Institute Inc). Statistical analyses were mainly performed using the SAS software package ver. The optimal Youden index-based cutoff point for MH was chosen to maximize the sum of sensitivity and specificity. A receiver operating characteristic (ROC) curve was generated, and the area under the curve (AUC) was calculated to indicate the utility of the AGR for MH. Age, sex, steroid use, BMI, onset age, and anti-tumor necrosis factor α (TNF-α) preparation and disease extent (proctitis/non-proctitis) were selected as confounding factors. Multiple logistic regression analyses were used to adjust for potential confounding factors. ![]() Estimations of crude odds ratios (ORs) and their 95% confidence intervals (CIs) for CR, complete MH, and MH in relation to AGR were performed using logistic regression analysis. ![]() CRP was divided into 2 categories based on the median value of CRP: low CRP of ≤ 0.1 mg/dL and high CRP of > 0.1 mg/dL). To investigate the exposure-response relationship between AGR and clinical outcomes, AGR level was classified into 4 categories: low AGR, 1.643. The 4 quartiles of AGR distribution in this study as follows: quartile 1 (n=67), 1.643. After these 114 patients were excluded due to incomplete data, the final analysis sample in this study consisted of 273 patients.ĪGR was divided into quartiles on the basis of the distribution of all study subjects. However, even after being informed about this study and agreeing to participate, some subjects did not agree to undergo the colonoscopy and blood test thus, some data are missing. Patients with newly diagnosed UC and acute severe UC were also included in this cohort. Consecutive outpatients and inpatients with UC who can understand our study were candidates. All patients were diagnosed with UC according to endoscopic, radiological, histological, and clinical criteria. The study subjects consisted of 387 Japanese patients with UC seen at the Department of Gastroenterology and Metabology of the Ehime University Graduate School of Medicine, and at several affiliated hospitals and clinics (Ehime Prefectural Central Hospital, Ehime Prefectural Niihama Hospital, Uwajima City Hospital, Saiseikai Matsuyama Hospital, Sumitomo Besshi Hospital, Saiseikai Imabari Hospital, and the OHASHI Clinic) in Ehime prefecture. - Copyright transfer agreement and conflict of interest disclosure.- Instructions for uploading manuscripts.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |